Synthesis and Photoinduced DNA Cleaving Activity of Hairpin Polyamide–Chlorobenzenesulfonyl Conjugate¶

Fei Li Tang; Gu Yuan; Jin Wang

doi:10.1562/0031-8655(2003)078<0175:SAPDCA>2.0.CO;2

We can help you reset your password using the email address linked to your BioOne Complete account.

Registered users receive a variety of benefits including the ability to customize email alerts, create favorite journals list, and save searches. Please note that a BioOne web account does not automatically grant access to full-text content. An institutional or society member subscription is required to view non-Open Access content. Contact helpdesk@bioone.org with any questions.

All Fields are Required

First Name

Last/Family Name

Password

Password Requirements: Minimum 8 characters, must include as least one uppercase, one lowercase letter, and one number or permitted symbol Valid Symbols for password:
~ Tilde
! Exclamation Mark
@ At sign
$ Dollar sign
^ Caret
( Opening Parenthesis
) Closing Parenthesis
_ Underscore
. Period

Confirm Password

Web Account created successfully

Fei Li Tang,¹ Gu Yuan,^1,* Jin Wang¹

¹Key Laboratory of Bioorganic Chemistry and Molecular Engineering of Education Ministry, Department o

^**To whom correspondence should be addressed at: Key Laboratory of Bioorganic Chemistry and Molecular Engineering of Education Ministry, Department of Chemical Biology, College of Chemistry, Peking University, Beijing 100871, People's Republic of China. Fax: 86-10-6275-1708; guyuan@pku.edu.cn

Abstract

A hairpin polyamide–chlorobenzenesulfonyl conjugate was synthesized in solution by a haloform reaction and the dicyclohexylcarbodiimide/1-hydroxybenzotriazole (DCC/HOBT) coupling reaction. Its ability to cleave DNA was investigated with supercoiled DNA (pBluescript SK), and the DNA cleaving efficiency of chlorobenzenesulfonyl group was enhanced by the hairpin polyamide under UV irradiation (365 nm).

Citation Download Citation

Fei Li Tang, Gu Yuan, and Jin Wang "Synthesis and Photoinduced DNA Cleaving Activity of Hairpin Polyamide–Chlorobenzenesulfonyl Conjugate," Photochemistry and Photobiology 78(2), 175-179, (1 August 2003). https://doi.org/10.1562/0031-8655(2003)078<0175:SAPDCA>2.0.CO;2

Received: 6 November 2002; Accepted: 1 February 2003; Published: 1 August 2003

This article is only available to subscribers.
It is not available for individual sale.

You currently do not have any folders to save your paper to! Create a new folder below.

Include:

Citation Only

Citation & Abstract

Format:

RIS

EndNote

BibTex

KEYWORDS/PHRASES

PUBLICATION TITLE:

COLLECTION:

PUBLICATION YEARS